Influence of endothelial function and arterial stiffness on the behavior of cervicocephalic arterial dissections: An observational study.

ABSTRACT:

Background

The mechanical and physiological properties of the arterial wall might affect the behavior of spontaneous cervicocephalic arterial dissections (CCAD). We aimed to determine the effects of endothelial function and arterial stiffness on the clinical characteristics and outcomes of CCAD using brachial flow-mediated dilation (FMD) and brachial-ankle pulse wave velocity (PWV).

Methods

From a single-center database, we identified patients admitted from April 2011 to December 2021 with a diagnosis of CCAD who underwent both FMD and PWV. FMD was classified as normal and decreased according to institutional thresholds. PWV was categorized into tertiles. Comparative and multivariable analyses were performed to determine the effects of FMD and PWV values on major clinical ou

SUBMITTER: Lee SJ 

PROVIDER: S-EPMC9464973 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature