Ontology highlight
ABSTRACT:
SUBMITTER: Lacroix B
PROVIDER: S-EPMC9465306 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Lacroix Benjamin B Lorca Thierry T Castro Anna A
Frontiers in cell and developmental biology 20220829
Cells require major physical changes to induce a proper repartition of the DNA. Nuclear envelope breakdown, DNA condensation and spindle formation are promoted at mitotic entry by massive protein phosphorylation and reversed at mitotic exit by the timely and ordered dephosphorylation of mitotic substrates. This phosphorylation results from the balance between the activity of kinases and phosphatases. The role of kinases in the control of mitosis has been largely studied, however, the impact of p ...[more]