High inflammatory burden predicts cardiovascular events in patients with axial spondyloarthritis: a long-term follow-up study.

ABSTRACT:

Background

Axial spondyloarthritis (axSpA) patients are at higher risk of cardiovascular (CV) disease (CVD) than the general population, partly due to consequences of inflammation or its treatment. But relationship between inflammation in axSpA and cardiovascular events (CVE) is unknown.

Objectives

To examine whether inflammatory burden over time can predict CVE independent of baseline CV risk factors in axSpA patients.

Design

A cohort analysis was performed in patients who had been recruited since January 2001. The primary outcome was a first CVE occurring between January 2001 and December 2020.

Methods

Three CVD risk scores were computed at baseline. The performance of the original and modified (*1.5 multiplication factor) CV risk algorithms were assessed. Ti

SUBMITTER: Shi LH 

PROVIDER: S-EPMC9465578 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature