Time to positivity of blood cultures in neonatal late-onset bacteraemia.

ABSTRACT:

Objective

To determine the time to positivity (TTP) of blood cultures among infants with late-onset bacteraemia and predictors of TTP >36 hours.

Design

Retrospective cohort study.

Setting

16 birth centres in two healthcare systems.

Patients

Infants with positive blood cultures obtained >72 hours after birth.

Outcome

The main outcome was TTP, defined as the time interval from specimen collection to when a neonatal provider was notified of culture growth. TTP analysis was restricted to the first positive culture per infant. Patient-specific and infection-specific factors were analysed for association with TTP >36 hours.

Results

Of 10 235 blood cultures obtained from 3808 infants, 1082 (10.6%) were positive. Restricting to bacterial pathogens and the

SUBMITTER: Mukhopadhyay S 

PROVIDER: S-EPMC9465986 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature