Correcting for base-population differences and unknown parent groups in single-step genomic predictions of Norwegian Red cattle.

ABSTRACT: Bias and inflation in genomic evaluation with the single-step methods have been reported in several studies. Incompatibility between the base-populations of the pedigree-based and the genomic relationship matrix (G) could be a reason for these biases. Inappropriate ways of accounting for missing parents could be another reason for biases in genetic evaluations with or without genomic information. To handle these problems, we fitted and evaluated a fixed covariate (J) that contains ones for genotyped animals and zeros for unrelated non-genotyped animals, or pedigree-based regression coefficients for related non-genotyped animals. We also evaluated alternative ways of fitting the J covariate together with genetic groups on biases and stability of breeding value estimates, and of including it

SUBMITTER: Belay TK 

PROVIDER: S-EPMC9467032 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature