Choriocapillaris flow deficit in a pachychoroid spectrum disease using en face optical coherence tomography angiography averaging.

ABSTRACT:

Purpose

To investigate the choriocapillaris changes associated with pachychoroid pigment epitheliopathy (PPE) in comparison with healthy eyes.

Methods

Nine 3 × 3 mm macular optical coherence tomography angiography images were acquired in patients with PPE and age-matched healthy participants. Multiple en face image averaging of the choriocapillaris was binarized for quantitative image analysis of the flow voids. In PPE eyes, we evaluated the presence of pachyvessels and the association between the location of the choriocapillaris flow deficit and pachyvessels.

Results

Thirty-two eyes with PPE and 30 eyes of healthy participants were included. In PPE eyes, the mean total area (1.16 ± 0.18 vs. 0.91 ± 0.16, p < 0.001) and average size of the flow voids (790 ± 144 vs. 520

SUBMITTER: Tagawa M 

PROVIDER: S-EPMC9467345 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature