Metagenomic detection of eumycetoma causative agents   from households of patients residing in two Sudanese endemic villages in White Nile State.

ABSTRACT: Eumycetoma is a chronic debilitating fungal disease endemic to tropical and subtropical regions, with Sudan featuring the highest eumycetoma incidence. Among the 50 species of fungi most commonly associated with eumycetoma Madurella mycetomatis (M. mycetomatis) is often referenced as the most common pathogen. However, there is an enormous knowledge gap related to this neglected disease and its pathogenesis, epidemiological features, and host-specific factors that could contribute to either the host susceptibility and resistance. In this study, we were able to utilize a metagenomic approach and samples collected from clinical black grains (BG) and familiar household environments aimed to assay both the habitat of eumycetoma-associated fungi and its possible connection with eumycetoma patien

SUBMITTER: Santona A 

PROVIDER: S-EPMC9467367 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature