Correlation of the systemic immune-inflammation index with short- and long-term prognosis after acute ischemic stroke.

ABSTRACT: Immune and inflammatory responses after stroke are important pathophysiological processes. This study explored the relationship between the systemic immune-inflammation index (SII) and stroke prognosis. Patients from the China National Stroke Registry III were investigated. SII was defined as neutrophils × platelets/lymphocytes, and the patients were divided into four groups according to quartiles based on SII values. The primary outcome was poor functional outcome, assessed by the modified Rankin Scale (mRS), defined as an mRS score of ≥3. The secondary outcome was the incidence of all-cause death and recurrent stroke. Data were analyzed using either the logistic regression or Cox regression models. As the SII quartile increased, the percentage of patients with poor functional outcomes in

SUBMITTER: Wang N 

PROVIDER: S-EPMC9467411 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature