Simultaneous affinity maturation and developability enhancement using natural liability-free CDRs.

ABSTRACT:

Abbreviations

CDR: complementarity determining region; FACS: fluorescence-activated cell sorting; k_a: association rate; k_d: dissociation rate; K_D: dissociation constant; scFv: single-chain variable fragment; SPR: surface plasmon resonance.

SUBMITTER: Teixeira AAR 

PROVIDER: S-EPMC9467613 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature