Layer-by-Layer Fabrication of PAH/PAMAM/Nano-CaCO₃ Composite Films and Characterization for Enhanced Biocompatibility.

ABSTRACT: Nanoparticle production and functionalization for various biomedical uses are still challenging. Polymer composites constituted of poly(amidoamine) (PAMAM), polyallylamine hydrochloride (PAH), and calcium carbonate (CaCO₃) nanoparticles have good biocompatibility with physiological tissue and fluids, making them excellent candidates for biomedical applications. This study investigated the characteristics of polymeric/nano-CaCO₃ composite films based on a PAH/PAMAM matrix, which were fabricated through layer-by-layer synthesis on quartz glass substrates. It was found that the as-prepared elastic moduli of the resultant (PAH/PAMAM) _n -CaCO₃ (where n represents the number of bilayers) composite films varied from 1.40 to 23.70 GPa for d

SUBMITTER: Shifeta NT 

PROVIDER: S-EPMC9467823 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature