An exploratory analysis of leukocyte telomere length among pregnant and non-pregnant people.

ABSTRACT:

Background

Leukocyte telomere length (LTL) is a biomarker that is affected by older age, psychosocial stress, and medical comorbidities. Despite the relevance of these factors to obstetric practice, little is known about LTL in pregnancy. Our study explored longitudinal LTL dynamics in pregnant and non-pregnant people.

Objective

This pilot study compares changes in LTL between pregnant and non-pregnant people over time, explores potential correlations between LTL and mental health measures, and investigates associations between short first-trimester LTL and adverse pregnancy outcomes.

Study design

This was a prospective pilot cohort study of nulliparous pregnant and non-pregnant people between ages 18 and 50 who presented for care at a single institution from January

SUBMITTER: Panelli DM 

PROVIDER: S-EPMC9467886 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature