Depletable peroxidase-like activity of Fe₃O₄ nanozymes accompanied with separate migration of electrons and iron ions.

ABSTRACT: As pioneering Fe₃O₄ nanozymes, their explicit peroxidase (POD)-like catalytic mechanism remains elusive. Although many studies have proposed surface Fe²⁺-induced Fenton-like reactions accounting for their POD-like activity, few have focused on the internal atomic changes and their contribution to the catalytic reaction. Here we report that Fe²⁺ within Fe₃O₄ can transfer electrons to the surface via the Fe²⁺-O-Fe³⁺ chain, regenerating the surface Fe²⁺ and enabling a sustained POD-like catalytic reaction. This process usually occurs with the outward migration of excess oxidized Fe³⁺ from the lattice, which is a rate-limiting step. After prolonged catalysis, Fe₃O₄

SUBMITTER: Dong H 

PROVIDER: S-EPMC9467987 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature