A meta-analysis of the long-term outcomes following surgery or endoscopic therapy for chronic pancreatitis.

ABSTRACT:

Purpose

Refractory abdominal pain is a cardinal symptom of chronic pancreatitis (CP). Management strategies revolve around pain mitigation and resolution. Emerging evidence from observational studies highlights that surgery may result in superior pain relief when compared to endoscopic therapy; however, its impact on long-term quality of life or functional outcome has yet to be determined.

Methods

A search through MEDLINE, PubMed and Web of Science was performed for RCTs that compared endoscopic treatment with surgery for the management of CP. The main outcome measure was the impact on pain control. Secondary outcome measures were the effect on quality of life and the incidence rate of new onset exocrine and endocrine failure. Data was pooled for analysis using either an odd

SUBMITTER: Hughes DL 

PROVIDER: S-EPMC9468079 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature