The role of peripheral blood eosinophil counts in acute Stanford type A aortic dissection patients.

ABSTRACT:

Background

Acute Stanford-A aortic dissection (AAAD) is a devastating cardiovascular condition with high mortality, therefore identifying risk prognosis factors is vital for the risk stratification of patients with AAAD. Here, we investigated peripheral blood eosinophil (EOS) counts in patients with AAAD and their possible biological implications.

Methods

We performed a single center retrospective cohort study. From 2011 to 2021, a total of 1,190 patients underwent AAAD surgery. Patients were categorized first by death and then admission EOS counts (0.00 × 10⁹/L or >0.00 × 10⁹/L). Demographics, laboratory data, and outcomes were analyzed using standard statistical analyses. Ascending aorta specimens were used for western blotting and histological assess

SUBMITTER: Qin X 

PROVIDER: S-EPMC9468214 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature