Nomogram for predicting the overall survival of patients with early-onset prostate cancer: A population-based retrospective study.

ABSTRACT:

Background

The incidence of early-onset prostate cancer (PCa) has increased significantly over the past few decades. It is necessary to develop a prognostic nomogram for the prediction of overall survival (OS) in early-onset PCa patients.

Methods

A total of 23,730 early-onset PCa patients (younger than 55 years old) between 2010 and 2015 in the Surveillance, Epidemiology, and End Results (SEER) database were enrolled for the current study, and randomly separated into the training cohort and the validation cohort. 361 eligible early-onset PCa patients from The Cancer Genome Atlas-Prostate Adenocarcinoma (TCGA-PRAD) cohort were obtained as the external validation cohort. Independent predictors were selected by univariate and multivariate Cox regression analysis, and a prognost

SUBMITTER: Hu Y 

PROVIDER: S-EPMC9468440 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature