Physiological changes and growth behavior of Corynebacterium glutamicum cells in biofilm.

ABSTRACT: Biofilm cells are well-known for their increased survival and metabolic capabilities and have been increasingly implemented in industrial and biotechnological processes. Corynebacterium glutamicum is one of the most widely used microorganisms in the fermentation industry. However, C. glutamicum biofilm has been rarely reported and little is known about its cellular basis. Here, the physiological changes and characteristics of C. glutamicum biofilm cells during long-term fermentation were studied for the first time. Results showed that the biofilm cells maintained stable metabolic activity and cell size was enlarged after repeated-batch of fermentation. Cell division was slowed, and chromosome content and cell proliferation efficiency were reduced during long-term ferme

SUBMITTER: Zhang D 

PROVIDER: S-EPMC9468548 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature