Supercritical CO₂ assisted extraction of essential oil and naringin from Citrus grandis peel: in vitro antimicrobial activity and docking study.

ABSTRACT: The extraction of bioactive compounds, including essential oils and flavonoids, using organic solvents is a significant environmental concern. In this work, waste C. grandis peel was the ingredient used to extract essential oil and naringin by conducting a supercritical CO₂ technique with a two stage process. In the first stage, the extraction with only supercritical CO₂ solvent showed a significant enhancement of the d-limonene component, up to 95.66% compared with the hydro-distillation extraction (87.60%). The extraction of naringin using supercritical CO₂ and ethanol as a co-solvent was done in the second stage of the process, followed by evaluating in vitro antimicrobial activity of both the essential oil and naringin. The essential oil i

SUBMITTER: Mai TC 

PROVIDER: S-EPMC9468803 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature