Procalcitonin and C-reactive protein in the diagnosis of spontaneous bacterial peritonitis.

ABSTRACT:

Background

Spontaneous bacterial peritonitis (SBP) is a serious complication of cirrhosis and is associated with high morbidity and mortality. Rapid institution of appropriate antibiotics is central to the improved patient outcome. Correctly obtaining ascites fluid for analysis has several technical and logistic limitations resulting in overuse of empiric antibiotics when patients are admitted to the hospital with suspected SBP. Procalcitonin and C-reactive protein (CRP) are non-invasive markers of infection. We conducted a study to illustrate the role of these markers in making the diagnosis of SBP in patients with cirrhosis.

Methods

A total of 45 patients were enrolled in this prospective cohort study, 14 (31.1%) of which were found to have SBP. Ascitic fluid neutrophils,

SUBMITTER: Verma R 

PROVIDER: S-EPMC9468983 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature