Azithromycin versus erythromycin infusions prior to endoscopy in upper gastrointestinal bleeding.

ABSTRACT:

Background

Intravenous erythromycin prior to endoscopy for upper gastrointestinal bleeding (GIB) improves outcomes but requires immediate preparation delaying administration in emergency cases. Azithromycin is readily available and does not require prolonged preparation. The aim of the study was to assess the effect of azithromycin in improving the quality of endoscopic visualization in upper GIB compared to erythromycin.

Methods

Patients admitted with upper GIB who received erythromycin or azithromycin before urgent endoscopy were included. Primary outcome of the quality of visualization was assessed by two gastroenterologists, blinded to the choice of infusion, using a scoring system ranging from 0 to 8, with a maximum of 2 points assigned to the fundus, body, antrum and b

SUBMITTER: Issa D 

PROVIDER: S-EPMC9468987 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature