Identifying optimal therapies in patients with advanced hepatocellular carcinoma: a systematic review and network meta-analysis.

ABSTRACT:

Background

Recently, increasing literature has been reported on optimal therapies in patients with advanced hepatocellular carcinoma (HCC) and many therapeutic modalities have been proposed to improve the survival rate. However, the results are not consistent due to different research protocols, small sample sizes and different study endpoints and there is no standard treatment protocol has been defined. Therefore, it is very important to explore the optimal bonding mode and to evaluate the efficacy and safety of the optimal sequential therapy for those patients.

Methods

We searched available databases through January 2020 for relevant studies. The main outcome measure was 1-year overall survival (OS) and overall response rate (ORR); the secondary outcome measure was a compo

SUBMITTER: Yang Z 

PROVIDER: S-EPMC9468989 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature