Emergence and Molecular Characterization of an Avian Hepatitis E Virus From Donglan Black Chicken in Southern China.

ABSTRACT: Avian hepatitis E virus (HEV) is a major pathogen associated with hepatitis splenomegaly syndrome in chickens and has been reported in China. Phylogenetic trees, Bayesian analysis, positive selection sites screening, and recombination analysis were first used to comprehend the global avian HEVs. All the avian HEV strains, including a new isolate named GX20A1 got from Donglan Black chicken in Guangxi, China, were uniformly defined into four genotypes, and GX20A1, belongs to Genotype 3. The topology of the phylogenetic tree based on the sequences of a 339-bp fragment (coding the helicase) in open reading frame (ORF) 1 of the avian HEVs was consistent with that based on the full-genome sequence. The estimated evolution rate of avian HEVs is 2.73 × 10^-3 substitution/site/year (95% c

SUBMITTER: Fu F 

PROVIDER: S-EPMC9469092 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature