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Synchronous duodenal neuroendocrine neoplasm and congenital factor XIII deficiency: case report and review of the literature.


ABSTRACT:

Background

Neuroendocrine neoplasms (NENs) are uncommon, with duodenal NENs (dNENs) being particularly rare in clinical practice. Congenital factor XIII deficiency (FXIIID) is also an extremely rare hematological disease in which poor wound healing may occur due to coagulopathy. The concurrent occurrence of these two rare diseases has not been reported before, which increases the difficulty of diagnosis and treatment. This is the first report of dNEN concomitant with Congenital FXIIID, which can present as a reference for clinicians who may encounter similar situations in the future.

Case description

We report a 33-year-old woman with bleeding diathesis since childhood who complained of digestive tract bleeding for 7 years. She was finally diagnosed as duodenal neuroendocrin

SUBMITTER: Shen L 

PROVIDER: S-EPMC9469169 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature