Association Between Patient-Reported Outcomes and Treatment Failure in Juvenile Idiopathic Arthritis.

ABSTRACT:

Objective

Children with juvenile idiopathic arthritis (JIA) frequently exhibit symptoms months before diagnosis. The aims of this study were to assess whether baseline patient-reported outcomes (PROs) are associated with changes in JIA pharmacotherapy treatment and whether symptom duration prior to JIA diagnosis is associated with disease activity scores over time.

Methods

This is a retrospective cohort study of patients with an incident diagnosis of JIA. Patient-reported symptom duration, pain, energy, disease activity, sleep, anxiety, and depression screenings, as well as provider-reported disease activity and joint count, were collected during routine clinical care. Cox proportional hazards evaluated PROs, disease activity scores, and symptom duration with initial medicat

SUBMITTER: Taxter A 

PROVIDER: S-EPMC9469478 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature