Characteristics of different asthma phenotypes associated with cough: a prospective, multicenter survey in China.

ABSTRACT:

Background

Asthma is a heterogeneous disease with variable symptoms, which presents with cough either as the sole or predominant symptom with or without wheezing. We compared the clinical and pathophysiological characteristics of cough predominant asthma (CPA), cough variant asthma (CVA) and classic asthma (CA) in order to determine any differential phenotypic traits.

Methods

In 20 clinics across China, a total of 2088 patients were finally recruited, including 327 CVA, 1041 CPA and 720 CA patients. We recorded cough and wheezing visual analogue scale, Leicester cough questionnaire (LCQ) and asthma control test scores. Fractional exhaled nitric oxide (FeNO), induced sputum cell counts, and capsaicin cough challenge were also measured and compared.

Results

CPA patients

SUBMITTER: Zhou J 

PROVIDER: S-EPMC9469623 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature