Associations between physiological and neural measures of sensory reactivity in youth with autism.

ABSTRACT:

Background

Individuals with Autism Spectrum Disorder (ASD) commonly show sensory over-responsivity (SOR), an impairing condition related to over-reactive brain and behavioral responses to aversive stimuli. While individuals with ASD often show atypically high physiological arousal, it is unclear how this relates to sensory reactivity. We therefore investigated how physiological arousal relates to brain and behavioral indices of SOR, to inform understanding of the biological mechanisms underlying SOR and to determine whether physiological measures are associated with SOR-related brain responses.

Methods

Youth aged 8-18 (49 ASD; 30 age- and performance-IQ-matched typically developing (TD)) experienced mildly aversive tactile and auditory stimuli first during functional magneti

SUBMITTER: Jung J 

PROVIDER: S-EPMC9469758 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature