Screening for Executive Dysfunction in Late-Life Depression: Utility of Trail Making Test and Self-Report Measures.

ABSTRACT:

Objective

Prior work suggests executive dysfunction (ED) on the Stroop Color and Word Test (SCWT) and the Mattis Dementia Rating Scale-2 Initiation/Perseveration subscale (DRS IP) predicts poor antidepressant response in late-life depression. This study examined if either patient perception of ED or the Trail Making Test Part B (TMT-B) could identify patients with impairment on the SCWT or DRS IP.

Methods

Patients were 65 or older and had a diagnosis of major depression without dementia. Cognition was assessed with the TMT-B, the SCWT, and the DRS IP. A self-reported Perceived Deficits Questionnaire (PDQ) subscale assessed patients' perceptions of ED.

Results

In 247 participants (mean age 71.3 years), the PDQ subscale was not associated with test performance. The sens

SUBMITTER: Bickford D 

PROVIDER: S-EPMC9469772 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature