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Glycopeptoid nanospheres: glycosylation-induced coacervation of poly(sarcosine).


ABSTRACT: Conjugation of maltopentaose to water-soluble homo-poly(sarcosine) induced self-association and formed nanospheres (-150 nm) in water although homo-poly(sarcosine) was water-soluble and did not form any aggregates. Fluorescent probe experiments showed that the spheres were non-ionic glycopeptoid coacervate-like particles with both hydrophobic and hydrophilic domains inside.

SUBMITTER: Okuno Y 

PROVIDER: S-EPMC9470024 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature