Local field potentials reflect cortical population dynamics in a region-specific and frequency-dependent manner.

ABSTRACT: The spiking activity of populations of cortical neurons is well described by the dynamics of a small number of population-wide covariance patterns, whose activation we refer to as 'latent dynamics'. These latent dynamics are largely driven by the same correlated synaptic currents across the circuit that determine the generation of local field potentials (LFPs). Yet, the relationship between latent dynamics and LFPs remains largely unexplored. Here, we characterised this relationship for three different regions of primate sensorimotor cortex during reaching. The correlation between latent dynamics and LFPs was frequency-dependent and varied across regions. However, for any given region, this relationship remained stable throughout the behaviour: in each of primary motor and premotor cortice

SUBMITTER: Gallego-Carracedo C 

PROVIDER: S-EPMC9470163 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature