Prognostic value and management of regional lymph nodes in locoregional breast cancer recurrence: a systematic review of the literature.

ABSTRACT:

Purpose

Management of regional lymph nodes in breast cancer recurrence has been heterogeneous. To facilitate clinical practice, this review aims to give an overview on the prognosis, staging and operative management of (inapparent) regional lymph nodes.

Methods

Current national and international guidelines are reviewed and a structured search of the literature between Jan 1, 1999 and Feb 1, 2021 on the repeat sentinel node biopsy (re-SNB) procedure was performed.

Results

Positive regional lymph nodes in recurrent breast cancer indicate a poorer outcome with axillary recurrences being the most favorable tumor site among all nodal regions. Most preferred staging method is ultrasound ± guided biopsy. PET-CT, scintimammography, SPECT-CT may improve visualization of affect

SUBMITTER: Ge I 

PROVIDER: S-EPMC9470629 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature