Impact of protocolized fluid management on electrolyte stability in patients undergoing continuous renal replacement therapy.

ABSTRACT:

Objective

Continuous renal replacement therapy (CRRT) is the standard treatment for critically ill patients with acute kidney injury (AKI). Electrolyte disturbance such as hypokalemia or hypophosphatemia occurs paradoxically in patients undergoing CRRT due to high clearance. We developed a fluid management protocol for dialysate and replacement fluid that depends on serum electrolytes and focuses on potassium and phosphate levels to prevent electrolyte disturbance during CRRT. The impact of our new fluid protocol on electrolyte stability was evaluated.

Methods

Adult patients who received CRRT between 2013 and 2017 were included. Patients treated 2 years before (2013-2014; pre-protocol group) and 2 years following development of the fluid protocol (2016-2017; protocol group)

SUBMITTER: Baeg SI 

PROVIDER: S-EPMC9471083 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature