Treatment and survival outcomes in older women with primary breast cancer: A retrospective propensity score-matched analysis.

ABSTRACT:

Purpose

Changes in biological features and functional status make management decisions in older women with primary breast cancer complicated. We aimed to provide an overview of the clinicopathological characteristics and survival outcomes of older breast cancer patients based on the current treatment strategies.

Methods

Female patients diagnosed with primary invasive breast cancer at Fudan University Shanghai Cancer Centre from 2008 to 2016 were included. Patients were divided into a younger group (<65 years) and older group (≥65 years). Propensity score matching was utilised to generate balanced cohorts.

Results

A total of 13,707 patients met the study criteria. Compared with younger patients, older patients had a higher Charlson Comorbidity Index (p < 0.001), less l

SUBMITTER: Sang Y 

PROVIDER: S-EPMC9471966 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature