Human amniotic membrane products for patients with diabetic foot ulcers. do they help? a systematic review and meta-analysis.

ABSTRACT:

Background

Diabetic foot ulcer (DFU) is one of the most serious diabetic complications. DFU is an open wound that usually occurs in the foot sole due to poor blood glucose control, peripheral neuropathy, and poor circulation. The human amniotic allograft membrane is a biological wound dressing derived from the amniotic membrane. It contains amino acids, nutrients, cytokines, and growth factors that make the growth process easier.

Objective

To compare dehydrated human amnion and chorion allograft (DHACA) plus the standard of wound care (SOC) with the SOC alone.

Methods

We searched for randomized clinical trials (RCTs) on PubMed, Scopus, Cochrane, and Web of Science till April 2021 using relevant keywords. All search results were screened for eligibility. We extracted t

SUBMITTER: Mohammed YA 

PROVIDER: S-EPMC9472416 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature