Inclusion body myositis: evolving concepts.

ABSTRACT:

Purpose of review

To discuss recent developments in our understanding of epidemiology, diagnostics, biomarkers, pathology, pathogenesis, outcome measures, and therapeutics in inclusion body myositis (IBM).

Recent findings

Recent epidemiology data confirms a relatively higher prevalence in the population aged above 50 years and the reduced life expectancy. Association with cancer and other systemic disorders is better defined. The role of magnetic resonance imaging (MRI) and ultrasound in diagnosis as well as in following disease progression has been elucidated. There are new blood and imaging biomarkers that show tremendous promise for diagnosis and as outcome measures in therapeutic trials. Improved understanding of the pathogenesis of the disease will lead to better therap

SUBMITTER: Perez-Rosendahl M 

PROVIDER: S-EPMC9472875 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature