Interfacial engineering of carbon dots with benzenediboronic acid for fluorescent biosensing.

ABSTRACT: Glucose assay is highly important in clinical diagnostics of diabetes. Herein, we engineered the surface of carbon dots by complexation with functional ligand and constructed fluorescent biosensors for the detection of hydrogen peroxide and glucose. In this study, benzenediboronic acid is conjugated to the surface of citric acid-derived carbon dots through formation of boronate complexes with the nanoparticles. The oxidation of benzenediboronic acid with hydrogen peroxide effectively quenches fluorescence of carbon dots through electron transfer process. The sensing performance of the system according to different engineered surfaces of carbon dots was studied by using carbon dots derived from various precursors and different benzenediboronic acid analogues. As a simple mix-and-detect stra

SUBMITTER: Pan M 

PROVIDER: S-EPMC9473241 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature