Preeclampsia has an association with both platelet count and mean platelet volume: A systematic review and meta-analysis.

ABSTRACT:

Background

Preeclampsia (PE) is a pregnancy-specific disorder characterized by endothelial dysfunction, and activation of the coagulation system. Alteration of PLT parameters is the common hematological abnormality observed in women with PE. The main aim of this study was to systematically review previous studies from around the world to generate evidence about the relationship between platelet count (PC) and PE, as well as mean platelet volume (MPV) and PE, by calculating the pooled weighted mean difference (WMD) of PC and MPV between PE and normotensive (NT) groups.

Methods

Relevant articles which were published in the English language from January 10, 2011, to January 10, 2021, were systematically searched through PubMed, Web of Science, and African journals online. In ad

SUBMITTER: Walle M 

PROVIDER: S-EPMC9473393 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature