Reproductive isolation via polygenic local adaptation in sub-divided populations: Effect of linkage disequilibria and drift.

ABSTRACT: This paper considers how polygenic local adaptation and reproductive isolation between hybridizing populations is influenced by linkage disequilibria (LD) between loci, in scenarios where both gene flow and genetic drift counteract selection. It shows that the combined effects of multi-locus LD and genetic drift on allele frequencies at selected loci and on heterozygosity at neutral loci are predicted accurately by incorporating (deterministic) effective migration rates into the diffusion approximation (for selected loci) and into the structured coalescent (for neutral loci). Theoretical approximations are tested against individual-based simulations and used to investigate conditions for the maintenance of local adaptation on an island subject to one-way migration from a differently adapte

SUBMITTER: Sachdeva H 

PROVIDER: S-EPMC9473638 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature