Benefit of endoscopic stenting for dominant strictures in patients with primary sclerosing cholangitis.

ABSTRACT: Background and study aims  Dominant strictures (DS) occur in up to 60 % of patients with primary sclerosing cholangitis (PSC). Data regarding the long-term effects of stenting vs. dilation remain limited. The aim of this study was to compare the two treatment modalities in terms of transplantation-free survival. Patients and methods  This single-center, retrospective study examined patients with PSC and DS treated endoscopically with a minimum of 1 year follow-up. Patients were divided into two cohorts: 1) those who received dilation alone; and 2) those who received both dilation and stenting. The primary outcome was transplantation-free survival, defined as time after index ERCP to liver transplantation. Results  In all, 169 patients (54 in dilation cohort, 115 in ste

SUBMITTER: Han S 

PROVIDER: S-EPMC9473835 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature