Long-term Outcomes Following Esophagectomy in Older and Younger Adults with Esophageal Cancer.

ABSTRACT:

Background

Patterns of overall and disease-free survival after esophagectomy for esophageal cancer in older adults have not been carefully studied.

Methods

Retrospective analysis of all patients with esophageal cancer undergoing esophagectomy from 2005 to 2020 at our institution was performed. Differences in outcomes were stratified by age groups, < 75 and ≥ 75 years old, and two time periods, 2005-2012 and 2013-2020.

Results

A total of 1135 patients were included: 979 (86.3%) patients were < 75 (86.3%), and 156 (13.7%) were ≥ 75 years old. Younger patients had fewer comorbidities, better nutritional status, and were more likely to receive neoadjuvant and adjuvant therapy (all p < 0.05). However, tumor stage and operative approach were similar, except for increased pe

SUBMITTER: Dezube AR 

PROVIDER: S-EPMC9474270 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature