Development of root resorption during orthodontic tooth movement after cleft repair using different grafting materials in rats.

ABSTRACT:

Objective

The aim of the present study was to investigate the influence of three grafting materials for cleft repair on orthodontic tooth movement in rats.

Materials and methods

Artificial alveolar clefts were created in 21 Wistar rats and were repaired 4 weeks later using autografts, human xenografts and synthetic bone substitute (beta-tricalcium phosphate/hydroxyapatite [β-TCP/HA]). A further 4 weeks later, the first molar was moved into the reconstructed maxilla. Microfocus computed tomography (μCT) was performed six times (T0-T5) to assess the tooth movement and root resorption. After 8 weeks, the affected reconstructed jaw was resected for histopathological investigation.

Results

Total distances reached ranged from 0.82 ± 0.72 mm (β-TCP/HA) to 0.67 ± 0.27 mm (aut

SUBMITTER: Mohlhenrich SC 

PROVIDER: S-EPMC9474460 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature