Excitatory and inhibitory neural dynamics jointly tune motion detection.

ABSTRACT: Neurons integrate excitatory and inhibitory signals to produce their outputs, but the role of input timing in this integration remains poorly understood. Motion detection is a paradigmatic example of this integration, since theories of motion detection rely on different delays in visual signals. These delays allow circuits to compare scenes at different times to calculate the direction and speed of motion. Different motion detection circuits have different velocity sensitivity, but it remains untested how the response dynamics of individual cell types drive this tuning. Here, we sped up or slowed down specific neuron types in Drosophila's motion detection circuit by manipulating ion channel expression. Altering the dynamics of individual neuron types upstream of motion detectors increased

SUBMITTER: Gonzalez-Suarez AD 

PROVIDER: S-EPMC9474608 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature