Development of a classifier for [18F]fluorodeoxyglucose extravasation severity using semi-quantitative readings from topically applied detectors.

ABSTRACT:

Background

Radiotracer extravasations, caused largely by faulty tracer injections, can occur in up to 23% of ¹⁸F-fluorodeoxyglucose (FDG) PET/CT scans and negatively impact radiological review and tracer quantification. Conventional radiological assessment of extravasation severity on PET has limited performance (e.g., extravasations frequently resolve before scanning) and practical drawbacks. In this study, we develop a new topical detector-based FDG extravasation severity classifier, calibrated from semi-quantitative PET measurements, and assess its performance on human subjects.

Methods

A retrospective study examined patients whose FDG injections had been monitored as part of their standard workup for PET/CT imaging. Topical uncollimated gamma ray detectors wer

SUBMITTER: Perrin S 

PROVIDER: S-EPMC9474785 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature