Lipoprotein (a) levels and vulnerable characteristics in nonculprit plaque in patients with acute coronary syndrome.

ABSTRACT:

Background

High plasma levels of Lp(a) are associated with a worse prognosis in patients with coronary artery disease. The aim of the present study is to clarify the association between high lipoprotein a [Lp(a)] levels and vulnerable characteristics of nonculprit plaques in patients with acute coronary syndrome (ACS).

Methods

A total of 185 consecutive patients with ACS who underwent optical coherence tomography imaging of nonculprit plaques in the culprit vessels were enrolled. Patients were divided into the high Lp(a) group (≥30 mg/dL; 50 nonculprit plaques in 49 patients) or the low Lp(a) group (<30 mg/dL; 139 nonculprit plaques in 136 patients).

Results

The prevalence of thin-cap fibroatheroma (TCFA) was significantly higher in the high Lp(a) group than in the lo

SUBMITTER: Kato A 

PROVIDER: S-EPMC9474856 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature