Comparison between a dual-time-window protocol and other simplified protocols for dynamic total-body ¹⁸F-FDG PET imaging.

ABSTRACT:

Purpose

Efforts have been made both to avoid invasive blood sampling and to shorten the scan duration for dynamic positron emission tomography (PET) imaging. A total-body scanner, such as the uEXPLORER PET/CT, can relieve these challenges through the following features: First, the whole-body coverage allows for noninvasive input function from the aortic arteries; second, with a dramatic increase in sensitivity, image quality can still be maintained at a high level even with a shorter scan duration than usual. We implemented a dual-time-window (DTW) protocol for a dynamic total-body ¹⁸F-FDG PET scan to obtain multiple kinetic parameters. The DTW protocol was then compared to several other simplified quantification methods for total-body FDG imaging that were proposed for

SUBMITTER: Wang Z 

PROVIDER: S-EPMC9474964 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature