Association of baseline level of cardiovascular risk burden and its temporal changes with cognitive decline.

ABSTRACT:

Background and aim

Previous studies on cardiovascular risk burden assessed by the Framingham General Cardiovascular Risk Score (FGCRS) and cognitive trajectories mainly focus on Western populations and most of them have used a single measure of cardiovascular risk. In this study, among middle-aged and older Chinese, we investigated (i) the association of baseline FGCRS with subsequent cognitive decline and (ii) the association of FGCRS change with concomitant cognitive decline.

Materials and methods

In wave 1 to wave 4 (2011-2018) of the China Health and Retirement Longitudinal Study, global cognition was assessed by orientation, memory, and executive function. FGCRS was assessed and categorized into tertiles (low, intermediate, and high) at baseline (2011) and 4 years after

SUBMITTER: Ji X 

PROVIDER: S-EPMC9474998 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature