White matter hyperintensities in Burning Mouth Syndrome assessed according to the Age-Related White Matter Changes scale.

ABSTRACT:

Background

White matter hyperintensities (WMHs) of the brain are observed in normal aging, in various subtypes of dementia and in chronic pain, playing a crucial role in pain processing. The aim of the study has been to assess the WMHs in Burning Mouth Syndrome (BMS) patients by means of the Age-Related White Matter Changes scale (ARWMCs) and to analyze their predictors.

Methods

One hundred BMS patients were prospectively recruited and underwent magnetic resonance imaging (MRI) of the brain. Their ARWMCs scores were compared with those of an equal number of healthy subjects matched for age and sex. Intensity and quality of pain, psychological profile, and blood biomarkers of BMS patients were further investigated to find potential predictors of WMHs. Specifically, the Numeri

SUBMITTER: Adamo D 

PROVIDER: S-EPMC9475000 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature