Stable functional compensation within hippocampal-subregion networks in patients with temporal glioma before and after surgery.

ABSTRACT:

Objective

To identify whether tumor invasion of the temporal lobe induces functional compensation of the hippocampal-subregion (HIPsub) network connectivity before surgery, and to further validate the stability of this functional compensation within the HIPsub network in patients with temporal glioma tumor (TTumor) after surgical resection of the tumor.

Methods

In the first cohort, analysis of HIPsub functional connectivity (FC) was conducted to identify the functional compensation of the altered HIPsub connectivity pattern in TTumor through a pattern classification approach. Then, the second cohort investigated whether functional compensation in TTumor patients changed after surgical resection of the tumor.

Results

In the first cohort, this study identified altered H

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9475067 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature