Impact of early Kasai portoenterostomy on short-term outcomes of biliary atresia: A systematic review and meta-analysis.

ABSTRACT:

Background

Good outcomes of biliary atresia (BA) are conventionally achieved after early Kasai portoenterostomy (KP). However, in some recent pieces of literature, there are discrepancies in the influence of age in Kasai procedure on postoperative short-term prognosis. This meta-analysis aims to evaluate the effects of earlier KP on short-term surgical prognosis of BA and clarify these discrepancies in recent studies.

Methods

To identify related studies, PubMed, Embase, Web of Science, Cochrane, and the Chinese National Knowledge Infrastructure database were searched up to March 2022. Data for the impact of age at KP on clinical prognosis were extracted, including jaundice clearance rate (JCR) and native liver survival rate (NLSR).

Results

A total of 14 articles were

SUBMITTER: Yang C 

PROVIDER: S-EPMC9475174 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature