Quantitative behavioral evaluation of a non-human primate stroke model using a new monitoring system.

ABSTRACT:

Background

Recently, the common marmoset (Callithrix jacchus) has attracted significant interest as a non-human primate stroke model. Functional impairment in non-human primate stroke models should be evaluated quantitatively and successively after stroke, but conventional observational assessments of behavior cannot fully fit this purpose. In this paper, we report a behavioral analysis using MarmoDetector, a three-dimensional motion analysis, in an ischemic stroke model using photosensitive dye, along with an observational behavioral assessment and imaging examination.

Methods

Ischemic stroke was induced in the left hemisphere of three marmosets. Cerebral infarction was induced by intravenous injection of rose bengal and irradiation with green light. The following da

SUBMITTER: Hirohata T 

PROVIDER: S-EPMC9475201 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature