Relationship between reward-related evoked potentials and real-world motivation in older people living with human immunodeficiency virus.

ABSTRACT: Apathy, a clinical disorder characterized by low motivation, is prevalent in people living with Human Immunodeficiency Virus (HIV). It affects mental and physical health-related quality-of-life, medication adherence, and is associated with cognitive decline. However, the causes of apathy and the underlying brain mechanisms in HIV are unknown. Brain responses to reward may be relevant to understanding apathy and might serve as biomarkers for diagnosis or treatment response. Electroencephalogram (EEG) responses to gain and loss feedback in simple guessing tasks have been related to apathy in neurodegenerative conditions and healthy individuals. The primary aim of this study is to contribute evidence regarding the relationship between two EEG correlates of reward processing, the Reward Positi

SUBMITTER: Castaneda G 

PROVIDER: S-EPMC9475288 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature