Introduction of Flavor Chemical Eugenol Attenuating the Synergistic Toxicological Interactions of Flavor Mixtures.

ABSTRACT: The flavor chemicals benzyl alcohol (BEA), phenylethanol (PHA), and cinnamaldehyde (CID) and their binary mixtures have high toxicity sensitivity to the lethal endpoint of Caenorhabditis elegans. Some binary flavor mixtures even have synergistic toxicological interactions. Eugenol (EUG) is closely related to human life and has many special nonlethal effects on organisms. The effect of its introduction on the combined toxicities of flavor mixtures is worth studying. We introduced EUG into three binary (BEA-PHA, BEA-CID, and PHA-CID) and one ternary (BEA-PHA-CID) flavor mixture systems. Five representative mixture rays were selected from each of the four mixture systems using the uniform design ray (UD-Ray) method. The lethal toxicity of each mixture ray to C. elegans was measu

SUBMITTER: Lu S 

PROVIDER: S-EPMC9475627 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature